Tapering Oral Steroid Treatment After IV Methylprednisolone Pulse Therapy in Demyelinating Optic Neuritis

Tapering Oral Steroid Treatment After IV Methylprednisolone Pulse Therapy in Demyelinating Optic Neuritis

Blog Article

Background: Optic neuritis is an inflammation of the optic nerve.Because of importance of vision for human, management beetroot birkenstock of optic neuritis is an important issue in neurology.Objectives: This study aimed at assessing the effect of oral steroid treatment after intravenous (IV) methylprednisolone therapy on demyelinating optic neuritis.Materials & Methods: 60 Patients with first episode of acute demyelinating optic neuritis who referred to a neurology clinic in an academic hospital in south-west of Iran in 2015-2016 included in this randomized double-blind clinical trial study (No: IRCT2015102724735N1).They were divided into two groups with (A) and without (B) tapering oral steroid treatment after IV methylprednisolone.

Visual acuity and color vision were measured before treatment, before oral tapering, 1 and 3 months after treatment.Independent t-test in SPSS software version 20 was used to analyze the data.P0.05).Frequency of color vision abnormality in groups A canine spectra kc 3 intranasal single dose and B were at baseline (53.

3% vs.56.6%) (P=0.796), before oral tapering (43.3% vs.

30%, P=0.284), 1 month after treatment (23.3% vs.30%, P=0.559), 3 months after treatment (0% vs.

23%, P=0.011).Conclusion: Oral steroid treatment after IV methylprednisolone pulse therapy improves color vision after 3 months in patients with demyelinating optic neuritis but has no effect on visual acuity.